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Structures of carbon catabolite protein A–(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators
In Gram-positive bacteria, carbon catabolite protein A (CcpA) is the master regulator of carbon catabolite control, which ensures optimal energy usage under diverse conditions. Unlike other LacI-GalR proteins, CcpA is activated for DNA binding by first forming a complex with the phosphoprotein HPr-S...
Autores principales: | Schumacher, Maria A., Sprehe, Mareen, Bartholomae, Maike, Hillen, Wolfgang, Brennan, Richard G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074128/ https://www.ncbi.nlm.nih.gov/pubmed/21106498 http://dx.doi.org/10.1093/nar/gkq1177 |
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