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Protein flexibility directs DNA recognition by the papillomavirus E2 proteins

Although DNA flexibility is known to play an important role in DNA–protein interactions, the importance of protein flexibility is less well understood. Here, we show that protein dynamics are important in DNA recognition using the well-characterized human papillomavirus (HPV) type 6 E2 protein as a...

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Detalles Bibliográficos
Autores principales: Brown, Craig, Campos-León, Karen, Strickland, Madeleine, Williams, Christopher, Fairweather, Victoria, Brady, R. Leo, Crump, Matthew P., Gaston, Kevin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074142/
https://www.ncbi.nlm.nih.gov/pubmed/21131281
http://dx.doi.org/10.1093/nar/gkq1217