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Sld2 binds to origin single-stranded DNA and stimulates DNA annealing

Sld2 is essential for the initiation of DNA replication, but the mechanism underlying its role in replication is not fully understood. The S-phase cyclin dependent kinase (S-CDK) triggers the association of Sld2 with Dpb11, and a phosphomimetic mutation of Sld2, Sld2T84D, functionally mimics the S-C...

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Detalles Bibliográficos
Autores principales:	Kanter, Diane M., Kaplan, Daniel L.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074145/ https://www.ncbi.nlm.nih.gov/pubmed/21109535 http://dx.doi.org/10.1093/nar/gkq1222

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