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Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature
INTRODUCTION: Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074556/ https://www.ncbi.nlm.nih.gov/pubmed/21435204 http://dx.doi.org/10.1186/1752-1947-5-114 |
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author | Porteous, Haldane Morgan, Nadia Lanfranco, Julio Garcia-Buitrago, Monica Young, Larry Lenz, Oliver |
author_facet | Porteous, Haldane Morgan, Nadia Lanfranco, Julio Garcia-Buitrago, Monica Young, Larry Lenz, Oliver |
author_sort | Porteous, Haldane |
collection | PubMed |
description | INTRODUCTION: Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus erythematosus complicated by type 4 renal tubular acidosis who did not do poorly. CASE PRESENTATION: A 44-year-old Hispanic woman developed a non-anion gap hyperkalemic metabolic acidosis consistent with type 4 renal tubular acidosis while being treated in the hospital for recently diagnosed systemic lupus erythematosus with multi-organ involvement. She responded well to treatment with corticosteroids, hydroxychloroquine and mycophenolate mofetil. Normal renal function was achieved prior to discharge and remained normal at the patient's one-month follow-up examination. CONCLUSION: This case increases awareness of an uncommon association between systemic lupus erythematosus and type 4 renal tubular acidosis and suggests a positive impact of early diagnosis and appropriate immunosuppressive treatment on the patient's outcome. |
format | Text |
id | pubmed-3074556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-30745562011-04-13 Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature Porteous, Haldane Morgan, Nadia Lanfranco, Julio Garcia-Buitrago, Monica Young, Larry Lenz, Oliver J Med Case Reports Case Report INTRODUCTION: Type 4 renal tubular acidosis is an uncommon clinical manifestation of systemic lupus erythematosus and has been reported to portend a poor prognosis. To the best of our knowledge, this is the first case report which highlights the successful management of a patient with systemic lupus erythematosus complicated by type 4 renal tubular acidosis who did not do poorly. CASE PRESENTATION: A 44-year-old Hispanic woman developed a non-anion gap hyperkalemic metabolic acidosis consistent with type 4 renal tubular acidosis while being treated in the hospital for recently diagnosed systemic lupus erythematosus with multi-organ involvement. She responded well to treatment with corticosteroids, hydroxychloroquine and mycophenolate mofetil. Normal renal function was achieved prior to discharge and remained normal at the patient's one-month follow-up examination. CONCLUSION: This case increases awareness of an uncommon association between systemic lupus erythematosus and type 4 renal tubular acidosis and suggests a positive impact of early diagnosis and appropriate immunosuppressive treatment on the patient's outcome. BioMed Central 2011-03-24 /pmc/articles/PMC3074556/ /pubmed/21435204 http://dx.doi.org/10.1186/1752-1947-5-114 Text en Copyright ©2011 Porteous et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Porteous, Haldane Morgan, Nadia Lanfranco, Julio Garcia-Buitrago, Monica Young, Larry Lenz, Oliver Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature |
title | Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature |
title_full | Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature |
title_fullStr | Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature |
title_full_unstemmed | Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature |
title_short | Systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature |
title_sort | systemic lupus erythematosus associated with type 4 renal tubular acidosis: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074556/ https://www.ncbi.nlm.nih.gov/pubmed/21435204 http://dx.doi.org/10.1186/1752-1947-5-114 |
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