The BRAF(V600E) mutation: what is it really orchestrating in thyroid cancer?

BRAF(V600E) is a constitutively active onco-kinase and is the most common genetic alteration in papillary thyroid carcinoma (PTC), and in anaplastic thyroid carcinoma as well, albeit at a lower frequency. The BRAF(V600E) mutation in some studies has been significantly associated with extra-thyroidal...

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Detalles Bibliográficos
Autores principales: Nucera, Carmelo, Lawler, Jack, Hodin, Richard, Parangi, Sareh
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074562/
https://www.ncbi.nlm.nih.gov/pubmed/21321384

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