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Gastric Varices with Remarkable Collateral Veins in Valpronic Acid-Induced Chronic Pancreatitis

Valproic acid (VPA) is a commonly prescribed and approved treatment for epilepsy, including Angelman syndrome, throughout the world. However, the long-term administration of drugs like VPA is associated with the possible development of gastric varices and splenic obstruction as a result of chronic p...

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Detalles Bibliográficos
Autores principales: Hattori, Y., Higurashi, T., Takahashi, H., Inamori, M., Abe, Y., Rino, Y., Nakajima, A.
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075155/
https://www.ncbi.nlm.nih.gov/pubmed/21490900
http://dx.doi.org/10.1159/000151288
Descripción
Sumario:Valproic acid (VPA) is a commonly prescribed and approved treatment for epilepsy, including Angelman syndrome, throughout the world. However, the long-term administration of drugs like VPA is associated with the possible development of gastric varices and splenic obstruction as a result of chronic pancreatitis. Such cases can be difficult to treat using endoscopy or interventional radiology because of hemodynamic abnormalities; therefore, surgical treatment is often necessary.