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Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient
We illustrate the case of a 41-year-old male with allergic manifestations since childhood. He sought medical attention for intermittent, progressive dysphagia from which he had been suffering for a number of years, having felt the sensation of a retrosternal lump and a self-limited obstruction to th...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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S. Karger AG
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075163/ https://www.ncbi.nlm.nih.gov/pubmed/21490835 http://dx.doi.org/10.1159/000113220 |
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author | Lucendo, Alfredo J. De Rezende, Livia Martín-Plaza, Jesús Larrauri, Javier |
author_facet | Lucendo, Alfredo J. De Rezende, Livia Martín-Plaza, Jesús Larrauri, Javier |
author_sort | Lucendo, Alfredo J. |
collection | PubMed |
description | We illustrate the case of a 41-year-old male with allergic manifestations since childhood. He sought medical attention for intermittent, progressive dysphagia from which he had been suffering for a number of years, having felt the sensation of a retrosternal lump and a self-limited obstruction to the passage of food. Endoscopy detected a submucosal tumor in the upper third of the esophagus, which was typified, via biopsy, as a granular cell tumor with benign characteristics and probably responsible for the symptoms. Two years later, the patient sought medical attention once again as these symptoms had not abated, hence digestive endoscopy was repeated. This revealed stenosis of the junction between the middle and lower thirds of the organ which had not been detected previously but was passable under gentle pressure. Eosinophilic esophagitis was detected after biopsies were taken. Esophageal manometry identified a motor disorder affecting the esophageal body. Following three months of treatment using fluticasone propionate applied topically, the symptoms went into remission, esophageal stenosis disappeared and the esophageal biopsies returned to normal. This is the first documented case of the link between granular cell tumors and Eosinophilic esophagitis, two different disorders which could cause dysphagia in young patients. |
format | Text |
id | pubmed-3075163 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-30751632011-04-13 Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient Lucendo, Alfredo J. De Rezende, Livia Martín-Plaza, Jesús Larrauri, Javier Case Rep Gastroenterol Published: February 2008 We illustrate the case of a 41-year-old male with allergic manifestations since childhood. He sought medical attention for intermittent, progressive dysphagia from which he had been suffering for a number of years, having felt the sensation of a retrosternal lump and a self-limited obstruction to the passage of food. Endoscopy detected a submucosal tumor in the upper third of the esophagus, which was typified, via biopsy, as a granular cell tumor with benign characteristics and probably responsible for the symptoms. Two years later, the patient sought medical attention once again as these symptoms had not abated, hence digestive endoscopy was repeated. This revealed stenosis of the junction between the middle and lower thirds of the organ which had not been detected previously but was passable under gentle pressure. Eosinophilic esophagitis was detected after biopsies were taken. Esophageal manometry identified a motor disorder affecting the esophageal body. Following three months of treatment using fluticasone propionate applied topically, the symptoms went into remission, esophageal stenosis disappeared and the esophageal biopsies returned to normal. This is the first documented case of the link between granular cell tumors and Eosinophilic esophagitis, two different disorders which could cause dysphagia in young patients. S. Karger AG 2008-02-05 /pmc/articles/PMC3075163/ /pubmed/21490835 http://dx.doi.org/10.1159/000113220 Text en Copyright © 2008 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published: February 2008 Lucendo, Alfredo J. De Rezende, Livia Martín-Plaza, Jesús Larrauri, Javier Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient |
title | Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient |
title_full | Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient |
title_fullStr | Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient |
title_full_unstemmed | Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient |
title_short | Esophageal Granular Cell Tumor and Eosinophilic Esophagitis: Two Interesting Entities Identified in the Same Patient |
title_sort | esophageal granular cell tumor and eosinophilic esophagitis: two interesting entities identified in the same patient |
topic | Published: February 2008 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075163/ https://www.ncbi.nlm.nih.gov/pubmed/21490835 http://dx.doi.org/10.1159/000113220 |
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