Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis

We report the first case of fatal bile duct necrosis following transcatheter arterial chemoembolization (TACE) in a 58-year-old woman. The patient underwent two TACEs to treat hepatic metastases from an ileal endocrine tumor. Persistent cholestasis occurred after the second procedure, leading to the...

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Autores principales: Pelletier, Anne-Laure, Hammel, Pascal, Zappa, Magali, Bedossa, Pierre, Rebours, Vinciane, Hentic, Olivia, Maire, Frédérique, Levy, Philippe, Ruszniewski, Philippe
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2008
Materias:
Published: November 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075197/
https://www.ncbi.nlm.nih.gov/pubmed/21490869
http://dx.doi.org/10.1159/000158542
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author Pelletier, Anne-Laure
Hammel, Pascal
Zappa, Magali
Bedossa, Pierre
Rebours, Vinciane
Hentic, Olivia
Maire, Frédérique
Levy, Philippe
Ruszniewski, Philippe
author_facet Pelletier, Anne-Laure
Hammel, Pascal
Zappa, Magali
Bedossa, Pierre
Rebours, Vinciane
Hentic, Olivia
Maire, Frédérique
Levy, Philippe
Ruszniewski, Philippe
author_sort Pelletier, Anne-Laure
collection PubMed
description We report the first case of fatal bile duct necrosis following transcatheter arterial chemoembolization (TACE) in a 58-year-old woman. The patient underwent two TACEs to treat hepatic metastases from an ileal endocrine tumor. Persistent cholestasis occurred after the second procedure, leading to the diagnosis of bile duct necrosis confirmed by liver biopsy. The patient died of liver failure with encephalopathy six months after the second TACE. Even though this complication is very rare, physicians should consider this diagnosis in patients who develop chronic, marked cholestasis following a TACE procedure.
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spelling pubmed-30751972011-04-13 Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis Pelletier, Anne-Laure Hammel, Pascal Zappa, Magali Bedossa, Pierre Rebours, Vinciane Hentic, Olivia Maire, Frédérique Levy, Philippe Ruszniewski, Philippe Case Rep Gastroenterol Published: November 2008 We report the first case of fatal bile duct necrosis following transcatheter arterial chemoembolization (TACE) in a 58-year-old woman. The patient underwent two TACEs to treat hepatic metastases from an ileal endocrine tumor. Persistent cholestasis occurred after the second procedure, leading to the diagnosis of bile duct necrosis confirmed by liver biopsy. The patient died of liver failure with encephalopathy six months after the second TACE. Even though this complication is very rare, physicians should consider this diagnosis in patients who develop chronic, marked cholestasis following a TACE procedure. S. Karger AG 2008-11-05 /pmc/articles/PMC3075197/ /pubmed/21490869 http://dx.doi.org/10.1159/000158542 Text en Copyright © 2008 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: November 2008
Pelletier, Anne-Laure
Hammel, Pascal
Zappa, Magali
Bedossa, Pierre
Rebours, Vinciane
Hentic, Olivia
Maire, Frédérique
Levy, Philippe
Ruszniewski, Philippe
Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis
title Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis
title_full Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis
title_fullStr Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis
title_full_unstemmed Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis
title_short Fatal Bile Duct Necrosis: A Rare Complication of Transcatheter Arterial Chemoembolization in a Patient with Endocrine Hepatic Metastasis
title_sort fatal bile duct necrosis: a rare complication of transcatheter arterial chemoembolization in a patient with endocrine hepatic metastasis
topic Published: November 2008
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075197/
https://www.ncbi.nlm.nih.gov/pubmed/21490869
http://dx.doi.org/10.1159/000158542
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