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Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report
A 60-year-old lady presented to us with a right upper abdominal mass. With a clinical diagnosis of liver tumor, she was evaluated with abdominal CT, MRI, nuclear scan, tumor markers, USG guided FNAC and other baseline investigations. On evaluation she had a massive right lobe tumor crossing the midl...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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S. Karger AG
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075202/ https://www.ncbi.nlm.nih.gov/pubmed/21490874 http://dx.doi.org/10.1159/000161563 |
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author | Ali, Sadaf Shah, Parveen Shah, Umer Javed Shah, Azra Zargar, Showkat Bashir, Atthar Dhar, Sunil Ali, Muzzafar |
author_facet | Ali, Sadaf Shah, Parveen Shah, Umer Javed Shah, Azra Zargar, Showkat Bashir, Atthar Dhar, Sunil Ali, Muzzafar |
author_sort | Ali, Sadaf |
collection | PubMed |
description | A 60-year-old lady presented to us with a right upper abdominal mass. With a clinical diagnosis of liver tumor, she was evaluated with abdominal CT, MRI, nuclear scan, tumor markers, USG guided FNAC and other baseline investigations. On evaluation she had a massive right lobe tumor crossing the midline. In view of the ambiguous diagnosis she was subjected to laparotomy where the lesion was judged unresectable and a biopsy was taken. Histopathological examination showed the rare pathology of primary fibrosarcoma of the liver with features of homogeneous, spindle-shaped cells with abundant collagen fibers showing a classic herringbone pattern. Tissue samples were then sent to another referral cancer hospital for immunohistochemistry and immunoreactive vimentin was found in the tumor cells. Electron microscopically, the tumor cells were rich in rough endoplasmic reticulum without a basement membrane, and were surrounded by large amounts of collagen fibers. The fibroblastic character of the tumor cells was suggested by light and electron microscopy. |
format | Text |
id | pubmed-3075202 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-30752022011-04-13 Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report Ali, Sadaf Shah, Parveen Shah, Umer Javed Shah, Azra Zargar, Showkat Bashir, Atthar Dhar, Sunil Ali, Muzzafar Case Rep Gastroenterol Published: November 2008 A 60-year-old lady presented to us with a right upper abdominal mass. With a clinical diagnosis of liver tumor, she was evaluated with abdominal CT, MRI, nuclear scan, tumor markers, USG guided FNAC and other baseline investigations. On evaluation she had a massive right lobe tumor crossing the midline. In view of the ambiguous diagnosis she was subjected to laparotomy where the lesion was judged unresectable and a biopsy was taken. Histopathological examination showed the rare pathology of primary fibrosarcoma of the liver with features of homogeneous, spindle-shaped cells with abundant collagen fibers showing a classic herringbone pattern. Tissue samples were then sent to another referral cancer hospital for immunohistochemistry and immunoreactive vimentin was found in the tumor cells. Electron microscopically, the tumor cells were rich in rough endoplasmic reticulum without a basement membrane, and were surrounded by large amounts of collagen fibers. The fibroblastic character of the tumor cells was suggested by light and electron microscopy. S. Karger AG 2008-11-08 /pmc/articles/PMC3075202/ /pubmed/21490874 http://dx.doi.org/10.1159/000161563 Text en Copyright © 2008 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published: November 2008 Ali, Sadaf Shah, Parveen Shah, Umer Javed Shah, Azra Zargar, Showkat Bashir, Atthar Dhar, Sunil Ali, Muzzafar Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report |
title | Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report |
title_full | Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report |
title_fullStr | Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report |
title_full_unstemmed | Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report |
title_short | Primary Fibrosarcoma of the Liver: We Don't Know Much: A Case Report |
title_sort | primary fibrosarcoma of the liver: we don't know much: a case report |
topic | Published: November 2008 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075202/ https://www.ncbi.nlm.nih.gov/pubmed/21490874 http://dx.doi.org/10.1159/000161563 |
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