Regulation of β-catenin by t-DARPP in upper gastrointestinal cancer cells

BACKGROUND: Truncated dopamine and cyclic-AMP-regulated phosphoprotein (t-DARPP) is frequently overexpressed in gastrointestinal malignancies. In this study, we examined the role of t-DARPP in regulating β-catenin. RESULTS: The pTopFlash construct that contains multiple TCF/LEF-binding sites was use...

Descripción completa

Detalles Bibliográficos
Autores principales: Vangamudi, Bhavatarini, Zhu, Shoumin, Soutto, Mohammed, Belkhiri, Abbes, El-Rifai, Wael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075216/
https://www.ncbi.nlm.nih.gov/pubmed/21447180
http://dx.doi.org/10.1186/1476-4598-10-32

Ejemplares similares

Ejemplares similares