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Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA editing targets in transcript 3′ UTRs

Apolipoprotein B-editing enzyme, catalytic polypeptide-1 (APOBEC1) is a cytidine deaminase, initially identified by its activity in converting a specific cytidine (C) to uridine (U) in apolipoprotein B (apoB) mRNA transcripts in the small intestine. Editing results in translation of a truncated apoB...

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Detalles Bibliográficos
Autores principales: Rosenberg, Brad R., Hamilton, Claire E., Mwangi, Michael M., Dewell, Scott, Papavasiliou, F. Nina
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075553/
https://www.ncbi.nlm.nih.gov/pubmed/21258325
http://dx.doi.org/10.1038/nsmb.1975