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Critical nucleus size for disease-related polyglutamine aggregation is repeat length dependent
Since polyglutamine (polyQ) aggregate formation has been implicated as playing an important role in expanded CAG repeat diseases, it is important to understand the biophysics underlying the initiation of aggregation. Previously we showed that relatively long polyQ peptides aggregate by nucleated gro...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075957/ https://www.ncbi.nlm.nih.gov/pubmed/21317897 http://dx.doi.org/10.1038/nsmb.1992 |