Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Induced Fibrosis

BACKGROUND AND AIM: The current study utilized a carbon tetrachloride (CCl(4))-induced liver fibrosis model to measure levels of the MMP9-mediated collagen type III degradation fragment CO3-610 (site of cleavage: KNGETGPQGP), during disease progression and regression, and to investigate a potential...

Descripción completa

Detalles Bibliográficos
Autores principales: Vassiliadis, Efstathios, Larsen, Dorthe Vang, Clausen, Rikke Elgaard, Veidal, Sanne Skovgård, Barascuk, Natasha, Larsen, Lise, Simonsen, Henrik, Segovia-Silvestre, Toni, Hansen, Christina, Overgaard, Trine, Leeming, Diana Julie, Karsdal, Morten A
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076019/
https://www.ncbi.nlm.nih.gov/pubmed/21499440
http://dx.doi.org/10.4137/BMI.S6347

Ejemplares similares

Ejemplares similares