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Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition Facilitates Epidermal Growth Factor-Dependent Breast Cancer Progression

TGF-β and EGF play critical roles in regulating the metastasis of aggressive breast cancers, yet the impact of epithelial-mesenchymal transition (EMT) induced by TGF-β in altering the response of breast cancer cells to EGF remains unknown. We show here that murine metastatic 4T1 breast cancer cells...

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Detalles Bibliográficos
Autores principales: Wendt, Michael K., Smith, Jason A., Schiemann, William P.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076082/
https://www.ncbi.nlm.nih.gov/pubmed/20802523
http://dx.doi.org/10.1038/onc.2010.377