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Controlling pH in shake flasks using polymer-based controlled-release discs with pre-determined release kinetics
BACKGROUND: There are significant differences in the culture conditions between small-scale screenings and large-scale fermentation processes. Production processes are usually conducted in fed-batch cultivation mode with active pH-monitoring and control. In contrast, screening experiments in shake f...
Autores principales: | Scheidle, Marco, Dittrich, Barbara, Klinger, Johannes, Ikeda, Hideo, Klee, Doris, Büchs, Jochen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076237/ https://www.ncbi.nlm.nih.gov/pubmed/21429210 http://dx.doi.org/10.1186/1472-6750-11-25 |
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