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The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro
BACKGROUND: Chondrosarcoma is virtually resistant to chemotherapy and radiation therapy. Survivin, the smallest member of the inhibitor of apoptosis protein family, is a critical factor for tumor progression and resistance to conventional therapeutic approaches in a wide range of malignancies. Howev...
Autores principales: | Lechler, Philipp, Renkawitz, Tobias, Campean, Valentina, Balakrishnan, Sanjeevi, Tingart, Markus, Grifka, Joachim, Schaumburger, Jens |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076263/ https://www.ncbi.nlm.nih.gov/pubmed/21457573 http://dx.doi.org/10.1186/1471-2407-11-120 |
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