Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications

FLT3 is a type III receptor tyrosine kinase. Mutations of FLT3 comprise one of the most frequently identified types of genetic alterations in acute myeloid leukemia. One-third of acute myeloid leukemia patients have mutations of this gene, and the majority of these mutations involve an internal tand...

Descripción completa

Detalles Bibliográficos
Autor principal: Takahashi, Shinichiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076284/
https://www.ncbi.nlm.nih.gov/pubmed/21453545
http://dx.doi.org/10.1186/1756-8722-4-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076284/
https://www.ncbi.nlm.nih.gov/pubmed/21453545
http://dx.doi.org/10.1186/1756-8722-4-13

Ejemplares similares