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The PlagL2 transcription factor activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells
Cytokine signaling pathways are frequent targets of oncogenic mutations in acute myeloid leukemia, promoting proliferation and survival. We have previously shown that the transcription factor PLAGL2 promotes proliferation and cooperates with the leukemia fusion protein Cbfβ-SMMHC in acute myeloid le...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076538/ https://www.ncbi.nlm.nih.gov/pubmed/21263445 http://dx.doi.org/10.1038/leu.2010.301 |