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Common variants in ZNF365 are associated with both mammographic density and breast cancer risk
High percent mammographic density adjusted for age and body mass index (BMI) is one of the strongest risk factors for breast cancer. We conducted a meta-analysis of five genome-wide association studies of percent mammographic density and report an association with rs10995190 in ZNF365 (combined P=9×...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
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2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076615/ https://www.ncbi.nlm.nih.gov/pubmed/21278746 http://dx.doi.org/10.1038/ng.760 |
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| author | Lindström, Sara Vachon, Celine M. Li, Jingmei Varghese, Jajini Thompson, Deborah Warren, Ruth Brown, Judith Leyland, Jean Audley, Tina Wareham, Nicholas J. Loos, Ruth J.F. Paterson, Andrew D. Waggott, Darryl Martin, Lisa J. Scott, Christopher G. Pankratz, V. Shane Hankinson, Susan E. Hazra, Aditi Hunter, David J. Hopper, John L. Southey, Melissa C. Chanock, Stephen J. Silva, Isabel dos Santos Liu, JianJun Eriksson, Louise Couch, Fergus J. Stone, Jennifer Apicella, Carmel Czene, Kamila Kraft, Peter Hall, Per Easton, Douglas F. Boyd, Norman F. Tamimi, Rulla M. |
| author_facet | Lindström, Sara Vachon, Celine M. Li, Jingmei Varghese, Jajini Thompson, Deborah Warren, Ruth Brown, Judith Leyland, Jean Audley, Tina Wareham, Nicholas J. Loos, Ruth J.F. Paterson, Andrew D. Waggott, Darryl Martin, Lisa J. Scott, Christopher G. Pankratz, V. Shane Hankinson, Susan E. Hazra, Aditi Hunter, David J. Hopper, John L. Southey, Melissa C. Chanock, Stephen J. Silva, Isabel dos Santos Liu, JianJun Eriksson, Louise Couch, Fergus J. Stone, Jennifer Apicella, Carmel Czene, Kamila Kraft, Peter Hall, Per Easton, Douglas F. Boyd, Norman F. Tamimi, Rulla M. |
| author_sort | Lindström, Sara |
| collection | PubMed |
| description | High percent mammographic density adjusted for age and body mass index (BMI) is one of the strongest risk factors for breast cancer. We conducted a meta-analysis of five genome-wide association studies of percent mammographic density and report an association with rs10995190 in ZNF365 (combined P=9×6·10(−10)). This finding might partly explain the underlying biology of the recently discovered association between common variants in ZNF365 and breast cancer risk. |
| format | Text |
| id | pubmed-3076615 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-30766152011-09-01 Common variants in ZNF365 are associated with both mammographic density and breast cancer risk Lindström, Sara Vachon, Celine M. Li, Jingmei Varghese, Jajini Thompson, Deborah Warren, Ruth Brown, Judith Leyland, Jean Audley, Tina Wareham, Nicholas J. Loos, Ruth J.F. Paterson, Andrew D. Waggott, Darryl Martin, Lisa J. Scott, Christopher G. Pankratz, V. Shane Hankinson, Susan E. Hazra, Aditi Hunter, David J. Hopper, John L. Southey, Melissa C. Chanock, Stephen J. Silva, Isabel dos Santos Liu, JianJun Eriksson, Louise Couch, Fergus J. Stone, Jennifer Apicella, Carmel Czene, Kamila Kraft, Peter Hall, Per Easton, Douglas F. Boyd, Norman F. Tamimi, Rulla M. Nat Genet Article High percent mammographic density adjusted for age and body mass index (BMI) is one of the strongest risk factors for breast cancer. We conducted a meta-analysis of five genome-wide association studies of percent mammographic density and report an association with rs10995190 in ZNF365 (combined P=9×6·10(−10)). This finding might partly explain the underlying biology of the recently discovered association between common variants in ZNF365 and breast cancer risk. 2011-01-30 2011-03 /pmc/articles/PMC3076615/ /pubmed/21278746 http://dx.doi.org/10.1038/ng.760 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms |
| spellingShingle | Article Lindström, Sara Vachon, Celine M. Li, Jingmei Varghese, Jajini Thompson, Deborah Warren, Ruth Brown, Judith Leyland, Jean Audley, Tina Wareham, Nicholas J. Loos, Ruth J.F. Paterson, Andrew D. Waggott, Darryl Martin, Lisa J. Scott, Christopher G. Pankratz, V. Shane Hankinson, Susan E. Hazra, Aditi Hunter, David J. Hopper, John L. Southey, Melissa C. Chanock, Stephen J. Silva, Isabel dos Santos Liu, JianJun Eriksson, Louise Couch, Fergus J. Stone, Jennifer Apicella, Carmel Czene, Kamila Kraft, Peter Hall, Per Easton, Douglas F. Boyd, Norman F. Tamimi, Rulla M. Common variants in ZNF365 are associated with both mammographic density and breast cancer risk |
| title | Common variants in ZNF365 are associated with both mammographic density and breast cancer risk |
| title_full | Common variants in ZNF365 are associated with both mammographic density and breast cancer risk |
| title_fullStr | Common variants in ZNF365 are associated with both mammographic density and breast cancer risk |
| title_full_unstemmed | Common variants in ZNF365 are associated with both mammographic density and breast cancer risk |
| title_short | Common variants in ZNF365 are associated with both mammographic density and breast cancer risk |
| title_sort | common variants in znf365 are associated with both mammographic density and breast cancer risk |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076615/ https://www.ncbi.nlm.nih.gov/pubmed/21278746 http://dx.doi.org/10.1038/ng.760 |
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