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Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

AIMS: Congenital long QT syndromes (LQTSs) are associated with prolonged ventricular repolarization and sudden cardiac death. Limitations to existing clinical therapeutic management strategies prompted us to develop a novel human in vitro drug-evaluation system for LQTS type 2 (LQT2) that will compl...

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Detalles Bibliográficos
Autores principales:	Matsa, Elena, Rajamohan, Divya, Dick, Emily, Young, Lorraine, Mellor, Ian, Staniforth, Andrew, Denning, Chris
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Fasttrack
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076668/ https://www.ncbi.nlm.nih.gov/pubmed/21367833 http://dx.doi.org/10.1093/eurheartj/ehr073

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