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Atorvastatin prevents age-related and amyloid-β-induced microglial activation by blocking interferon-γ release from natural killer cells in the brain

BACKGROUND: Microglial function is modulated by several factors reflecting the numerous receptors expressed on the cell surface, however endogenous factors which contribute to the age-related increase in microglial activation remain largely unknown. One possible factor which may contribute is interf...

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Detalles Bibliográficos
Autores principales: Lyons, Anthony, Murphy, Kevin J, Clarke, Rachael, Lynch, Marina A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077319/
https://www.ncbi.nlm.nih.gov/pubmed/21453520
http://dx.doi.org/10.1186/1742-2094-8-27