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HIV integrase variability and genetic barrier in antiretroviral naïve and experienced patients

BACKGROUND: HIV-1 integrase (IN) variability in treatment naïve patients with different HIV-1 subtypes is a major issue. In fact, the effect of previous exposure to antiretrovirals other than IN inhibitors (INI) on IN variability has not been satisfactorily defined. In addition, the genetic barrier...

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Detalles Bibliográficos
Autores principales: Piralla, Antonio, Paolucci, Stefania, Gulminetti, Roberto, Comolli, Giuditta, Baldanti, Fausto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077329/
https://www.ncbi.nlm.nih.gov/pubmed/21453487
http://dx.doi.org/10.1186/1743-422X-8-149

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