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A New Model to Produce Infectious Hepatitis C Virus without the Replication Requirement
Numerous constraints significantly hamper the experimental study of hepatitis C virus (HCV). Robust replication in cell culture occurs with only a few strains, and is invariably accompanied by adaptive mutations that impair in vivo infectivity/replication. This problem complicates the production and...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077361/ https://www.ncbi.nlm.nih.gov/pubmed/21533214 http://dx.doi.org/10.1371/journal.ppat.1001333 |