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Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation
Obesity is characterized by accumulation of excess body fat, while lipodystrophy is characterized by loss or absence of body fat. Despite their opposite phenotypes, these two conditions both cause ectopic lipid storage in non-adipose tissues, leading to lipotoxicity, which has health-threatening con...
Autores principales: | Tian, Yuan, Bi, Junfeng, Shui, Guanghou, Liu, Zhonghua, Xiang, Yanhui, Liu, Yuan, Wenk, Markus R., Yang, Hongyuan, Huang, Xun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077376/ https://www.ncbi.nlm.nih.gov/pubmed/21533227 http://dx.doi.org/10.1371/journal.pgen.1001364 |
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