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Characterization of Structural Features Controlling the Receptiveness of Empty Class II MHC Molecules
MHC class II molecules (MHC II) play a pivotal role in the cell-surface presentation of antigens for surveillance by T cells. Antigen loading takes place inside the cell in endosomal compartments and loss of the peptide ligand rapidly leads to the formation of a non-receptive state of the MHC molecu...
Autores principales: | Rupp, Bernd, Günther, Sebastian, Makhmoor, Talat, Schlundt, Andreas, Dickhaut, Katharina, Gupta, Shashank, Choudhary, Iqbal, Wiesmüller, Karl-Heinz, Jung, Günther, Freund, Christian, Falk, Kirsten, Rötzschke, Olaf, Kühne, Ronald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077389/ https://www.ncbi.nlm.nih.gov/pubmed/21533180 http://dx.doi.org/10.1371/journal.pone.0018662 |
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