Cargando…

Characterization of Structural Features Controlling the Receptiveness of Empty Class II MHC Molecules

MHC class II molecules (MHC II) play a pivotal role in the cell-surface presentation of antigens for surveillance by T cells. Antigen loading takes place inside the cell in endosomal compartments and loss of the peptide ligand rapidly leads to the formation of a non-receptive state of the MHC molecu...

Descripción completa

Detalles Bibliográficos
Autores principales: Rupp, Bernd, Günther, Sebastian, Makhmoor, Talat, Schlundt, Andreas, Dickhaut, Katharina, Gupta, Shashank, Choudhary, Iqbal, Wiesmüller, Karl-Heinz, Jung, Günther, Freund, Christian, Falk, Kirsten, Rötzschke, Olaf, Kühne, Ronald
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077389/
https://www.ncbi.nlm.nih.gov/pubmed/21533180
http://dx.doi.org/10.1371/journal.pone.0018662

Ejemplares similares