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Positive Autoregulation Delays the Expression Phase of Mammalian Clock Gene Per2
In mammals, cellular circadian rhythms are generated by a transcriptional-translational autoregulatory network that consists of clock genes that encode transcriptional regulators. Of these clock genes, Period1 (Per1) and Period2 (Per2) are essential for sustainable circadian rhythmicity and photic e...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077398/ https://www.ncbi.nlm.nih.gov/pubmed/21533189 http://dx.doi.org/10.1371/journal.pone.0018663 |