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Positive Autoregulation Delays the Expression Phase of Mammalian Clock Gene Per2
In mammals, cellular circadian rhythms are generated by a transcriptional-translational autoregulatory network that consists of clock genes that encode transcriptional regulators. Of these clock genes, Period1 (Per1) and Period2 (Per2) are essential for sustainable circadian rhythmicity and photic e...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077398/ https://www.ncbi.nlm.nih.gov/pubmed/21533189 http://dx.doi.org/10.1371/journal.pone.0018663 |