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Response of Estrogen Receptor-Positive Breast Cancer Tumorspheres to Antiestrogen Treatments
Estrogen signaling plays a critical role in the pathogenesis of breast cancer. Because the majority of breast carcinomas express the estrogen receptor ERα, endocrine therapy that impedes estrogen-ER signaling reduces breast cancer mortality and has become a mainstay of breast cancer treatment. Howev...
Autores principales: | Ao, Ada, Morrison, Brian J., Wang, Heiman, López, J. Alejandro, Reynolds, Brent A., Lu, Jianrong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077404/ https://www.ncbi.nlm.nih.gov/pubmed/21533195 http://dx.doi.org/10.1371/journal.pone.0018810 |
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