Cargando…

Crystal structure of a potassium ion transporter TrkH

The TrkH/TrkG/KtrB proteins mediate K(+) uptake in bacteria and likely evolved from simple K(+) channels by multiple gene duplications or fusions. Here we present the crystal structure of a TrkH from Vibrio parahaemolyticus. TrkH is a homodimer, and each protomer contains an ion permeation pathway....

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Yu, Jin, Xiangshu, Huang, Hua, Derebe, Mehabaw Getahun, Levin, Elena J., Kabaleeswaran, Venkataraman, Pan, Yaping, Punta, Marco, Love, James, Weng, Jun, Quick, Matthias, Ye, Sheng, Kloss, Brian, Bruni, Renato, Martinez-Hackert, Erik, Hendrickson, Wayne A., Rost, Burkhard, Javitch, Jonathan A., Rajashankar, Kanagalaghatta R., Jiang, Youxing, Zhou, Ming
Formato:	Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077569/ https://www.ncbi.nlm.nih.gov/pubmed/21317882 http://dx.doi.org/10.1038/nature09731

Ejemplares similares

Gating of the TrkH Ion Channel by its Associated RCK Protein, Trka
por: Cao, Yu, et al.
Publicado: (2013)

TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential
por: Zhang, Hanzhi, et al.
Publicado: (2020)

Two Trk/Ktr/HKT-type potassium transporters, TrkG and TrkH, perform distinct functions in Escherichia coli K-12
por: Tanudjaja, Ellen, et al.
Publicado: (2022)

Structural implications of weak Ca(2+) block in Drosophila cyclic nucleotide–gated channels
por: Lam, Yee Ling, et al.
Publicado: (2015)

Identification of trkH, Encoding a Potassium Uptake Protein Required for Francisella tularensis Systemic Dissemination in Mice
por: Alkhuder, Khaled, et al.
Publicado: (2010)

Environmental potassium regulates bacterial flotation, antibiotic production and turgor pressure in Serratia through the TrkH transporter
por: Quintero‐Yanes, Alex, et al.
Publicado: (2019)

Structure-based analysis of CysZ-mediated cellular uptake of sulfate
por: Assur Sanghai, Zahra, et al.
Publicado: (2018)

Homolog Structure of the SLAC1 Anion Channel for Closing Stomata in Leaves
por: Chen, Yuhang, et al.
Publicado: (2010)

Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel
por: Kong, Chunguang, et al.
Publicado: (2012)

Structural genomics target selection for the New York consortium on membrane protein structure
por: Punta, Marco, et al.
Publicado: (2009)

Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis
por: Ardiccioni, Chiara, et al.
Publicado: (2016)

Fluoride ion encapsulation by Mg(2+) and phosphates in a fluoride riboswitch
por: Ren, Aiming, et al.
Publicado: (2012)

In Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform
por: Venkataramani, Sathya, et al.
Publicado: (2020)

Crystal structure of group II intron domain 1 reveals a template for RNA assembly
por: Zhao, Chen, et al.
Publicado: (2015)

FcγRII-binding Centyrins mediate agonism and antibody-dependent cellular phagocytosis when fused to an anti-OX40 antibody
por: Zhang, Di, et al.
Publicado: (2018)

An estimated 5% of new protein structures solved today represent a new Pfam family
por: Mistry, Jaina, et al.
Publicado: (2013)

Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26–APC6 structure
por: Wang, Jing, et al.
Publicado: (2009)

Crystal structure of a eukaryotic group II intron lariat
por: Robart, Aaron R., et al.
Publicado: (2014)

Structures of NS5 Methyltransferase from Zika Virus
por: Coloma, Javier, et al.
Publicado: (2016)

Improved Disorder Prediction by Combination of Orthogonal Approaches
por: Schlessinger, Avner, et al.
Publicado: (2009)

Structure–function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2
por: Chen, Shoudeng, et al.
Publicado: (2015)

Solving nucleic acid structures by molecular replacement: examples from group II intron studies
por: Marcia, Marco, et al.
Publicado: (2013)

Structural basis for catalysis in a CDP-alcohol phosphotransferase
por: Sciara, Giuliano, et al.
Publicado: (2014)

Structural basis for the second step of group II intron splicing
por: Chan, Russell T., et al.
Publicado: (2018)

Structural basis for phosphatidylinositol-phosphate biosynthesis
por: Clarke, Oliver B., et al.
Publicado: (2015)

Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain
por: Jain, Rinku, et al.
Publicado: (2014)

TRK inhibitors in TRK fusion-positive cancers
por: Drilon, A
Publicado: (2019)

Structural basis of the alternating-access mechanism in a bile acid transporter
por: Zhou, Xiaoming, et al.
Publicado: (2013)

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport
por: Long, Feng, et al.
Publicado: (2010)

X-ray Structure of a Mammalian Stearoyl-CoA Desaturase
por: Bai, Yonghong, et al.
Publicado: (2015)

TrkA Co-Receptors: The Janus Face of TrkA?
por: Trouvilliez, Sarah, et al.
Publicado: (2023)

Structure and mechanism of human PrimPol, a DNA polymerase with primase activity
por: Rechkoblit, Olga, et al.
Publicado: (2016)

Selective activation and down‐regulation of Trk receptors by neurotrophins in human neurons co‐expressing TrkB and TrkC
por: Ateaque, Sarah, et al.
Publicado: (2022)

New Insights into the Hendra Virus Attachment and Entry Process from Structures of the Virus G Glycoprotein and Its Complex with Ephrin-B2
por: Xu, Kai, et al.
Publicado: (2012)

Basket trial of TRK inhibitors demonstrates efficacy in TRK fusion-positive cancers
por: Chen, Yu, et al.
Publicado: (2018)

Combinatorial Assembly of Small Molecules into Bivalent Antagonists of TrkC or TrkA Receptors
por: Brahimi, Fouad, et al.
Publicado: (2014)

Crystal structure of the Alcanivorax borkumensis YdaH transporter reveals an unusual topology
por: Bolla, Jani Reddy, et al.
Publicado: (2015)

HEP.TrkX [Vidyo]
por: Anderson, Dustin James
Publicado: (2017)

Signal Transduction Pathways through TRK‐A and TRK‐B Receptors in Human Neuroblastoma Cells
por: Sugimoto, Tohru, et al.
Publicado: (2001)

TRK inhibitors block NFKB and induce NRF2 in TRK fusion-positive colon cancer
por: Sohn, Sung-Hwa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_90u6t0mfgphm5egnvvitqglehb