Cargando…
The Anti-angiogenic Peptide Anginex Greatly Enhances Galectin-1 Binding Affinity for Glycoproteins
Angiogenesis is a key event in cancer progression and therefore a promising target in cancer treatment. Galectin-1, a β-galactoside binding lectin, is up-regulated in the endothelium of tumors of different origin and has been shown to be the target for anginex, a powerful anti-angiogenic peptide wit...
Autores principales: | Salomonsson, Emma, Thijssen, Victor L., Griffioen, Arjan W., Nilsson, Ulf J., Leffler, Hakon |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077580/ https://www.ncbi.nlm.nih.gov/pubmed/21372130 http://dx.doi.org/10.1074/jbc.C111.229096 |
Ejemplares similares
-
Ligand Induced Galectin-3 Protein Self-association
por: Lepur, Adriana, et al.
Publicado: (2012) -
Chemokines modulate glycan binding and the immunoregulatory activity of galectins
por: Sanjurjo, Lucía, et al.
Publicado: (2021) -
Galectin-8 in IgA Nephritis: Decreased Binding of IgA by Galectin-8 Affinity Chromatography and Associated Increased Binding in Non-IgA Serum Glycoproteins
por: Carlsson, Michael C., et al.
Publicado: (2011) -
Mutational Tuning of Galectin-3 Specificity and Biological Function
por: Salomonsson, Emma, et al.
Publicado: (2010) -
Ligand Sulfur
Oxidation State Progressively Alters
Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing
Hydrogen Bonds
por: Mahanti, Mukul, et al.
Publicado: (2023)