Small Ubiquitin-related Modifier Ligase Activity of Mms21 Is Required for Maintenance of Chromosome Integrity during the Unperturbed Mitotic Cell Division Cycle in Saccharomyces cerevisiae

The SUMO ligase activity of Mms21/Nse2, a conserved member of the Smc5/6 complex, is required for resisting extrinsically induced genotoxic stress. We report that the Mms21 SUMO ligase activity is also required during the unchallenged mitotic cell cycle in Saccharomyces cerevisiae. SUMO ligase-defec...

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Detalles Bibliográficos
Autores principales: Rai, Ragini, Varma, Satya P. M. V., Shinde, Nikhil, Ghosh, Shilpa, Kumaran, Srikala P., Skariah, Geena, Laloraya, Shikha
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077650/
https://www.ncbi.nlm.nih.gov/pubmed/21324902
http://dx.doi.org/10.1074/jbc.M110.157149

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