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Interbilayer-Crosslinked Multilamellar Vesicles as Synthetic Vaccines for Potent Humoral and Cellular Immune Responses
Vaccines based on recombinant proteins avoid toxicity and anti-vector immunity associated with live vaccine (e.g., viral) vectors, but their immunogenicity is poor, particularly for CD8(+) T-cell (CD8T) responses. Synthetic particles carrying antigens and adjuvant molecules have been developed to en...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077947/ https://www.ncbi.nlm.nih.gov/pubmed/21336265 http://dx.doi.org/10.1038/nmat2960 |