Dampening of death pathways by Schnurri 2 is essential for T cell development

Generation of a diverse and self-tolerant T cell repertoire requires appropriate interpretation of T cell receptor (TCR) signals by CD4(+)CD8(+) double positive (DP) thymocytes. Thymocyte cell fate is dictated by the nature of TCR:MHC-peptide interactions, with signals of higher strength leading to...

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Detalles Bibliográficos
Autores principales: Staton, Tracy L., Lazarevic, Vanja, Jones, Dallas C., Lanser, Amanda J., Takagi, Tsuyoshi, Ishii, Shunsuke, Glimcher, Laurie H.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077958/
https://www.ncbi.nlm.nih.gov/pubmed/21475200
http://dx.doi.org/10.1038/nature09848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077958/
https://www.ncbi.nlm.nih.gov/pubmed/21475200
http://dx.doi.org/10.1038/nature09848

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