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Dampening of death pathways by Schnurri 2 is essential for T cell development
Generation of a diverse and self-tolerant T cell repertoire requires appropriate interpretation of T cell receptor (TCR) signals by CD4(+)CD8(+) double positive (DP) thymocytes. Thymocyte cell fate is dictated by the nature of TCR:MHC-peptide interactions, with signals of higher strength leading to...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077958/ https://www.ncbi.nlm.nih.gov/pubmed/21475200 http://dx.doi.org/10.1038/nature09848 |