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Gfer inhibits Jab1-mediated degradation of p27(kip1) to restrict proliferation of hematopoietic stem cells

Growth factor erv1-like (Gfer) is an evolutionarily conserved sulfhydryl oxidase that is enriched in embryonic and adult stem cells and plays an essential prosurvival role in pluripotent embryonic stem cells. Here we show that knockdown (KD) of Gfer in hematopoietic stem cells (HSCs) compromises the...

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Detalles Bibliográficos
Autores principales:	Teng, Ellen C., Todd, Lance R., Ribar, Thomas J., Lento, William, Dimascio, Leah, Means, Anthony R., Sankar, Uma
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078070/ https://www.ncbi.nlm.nih.gov/pubmed/21346186 http://dx.doi.org/10.1091/mbc.E10-08-0723

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