Necessity of Hippocampal Neurogenesis for the Therapeutic Action of Antidepressants in Adult Nonhuman Primates

BACKGROUND: Rodent studies show that neurogenesis is necessary for mediating the salutary effects of antidepressants. Nonhuman primate (NHP) studies may bridge important rodent findings to the clinical realm since NHP-depression shares significant homology with human depression and kinetics of prima...

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Detalles Bibliográficos
Autores principales: Perera, Tarique D., Dwork, Andrew J., Keegan, Kathryn A., Thirumangalakudi, Lakshmi, Lipira, Cecilia M., Joyce, Niamh, Lange, Christopher, Higley, J. Dee, Rosoklija, Gorazd, Hen, Rene, Sackeim, Harold A., Coplan, Jeremy D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078107/
https://www.ncbi.nlm.nih.gov/pubmed/21525974
http://dx.doi.org/10.1371/journal.pone.0017600

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