Antigen-Specific Monoclonal Antibodies Isolated from B Cells Expressing Constitutively Active STAT5

BACKGROUND: Fully human monoclonal antibodies directed against specific pathogens have a high therapeutic potential, but are difficult to generate. METHODOLOGY/PRINCIPAL FINDINGS: Memory B cells were immortalized by expressing an inducible active mutant of the transcription factor Signal Transducer...

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Detalles Bibliográficos
Autores principales: Scheeren, Ferenc A., van Geelen, Caroline M. M., Yasuda, Etsuko, Spits, Hergen, Beaumont, Tim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078118/
https://www.ncbi.nlm.nih.gov/pubmed/21525985
http://dx.doi.org/10.1371/journal.pone.0017189

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