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Replication-Fork Stalling and Processing at a Single Psoralen Interstrand Crosslink in Xenopus Egg Extracts

Interstrand crosslink (ICL)-inducing agents block the separation of the two DNA strands. They prevent transcription and replication and are used in clinics for the treatment of cancer and skin diseases. Here, we have introduced a single psoralen ICL at a specific site in plasmid DNA using a triplex-...

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Detalles Bibliográficos
Autores principales:	Le Breton, Cyrille, Hennion, Magali, Arimondo, Paola B., Hyrien, Olivier
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078125/ https://www.ncbi.nlm.nih.gov/pubmed/21525992 http://dx.doi.org/10.1371/journal.pone.0018554

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