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Rosmarinic Acid, Active Component of Dansam-Eum Attenuates Ototoxicity of Cochlear Hair Cells through Blockage of Caspase-1 Activity
Cisplatin causes auditory impairment due to the apoptosis of auditory hair cells. There is no strategy to regulate ototoxicity by cisplatin thus far. Dansam-Eum (DSE) has been used for treating the central nerve system injury including hearing loss in Korea. However, disease-related scientific inves...
Autores principales: | Jeong, Hyun-Ja, Choi, Youngjin, Kim, Min-Ho, Kang, In-Cheol, Lee, Jeong-Han, Park, Channy, Park, Raekil, Kim, Hyung-Min |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078149/ https://www.ncbi.nlm.nih.gov/pubmed/21526214 http://dx.doi.org/10.1371/journal.pone.0018815 |
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