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How to be a mitotic chromosome

Proper mitotic chromosome structure is essential for faithful chromosome segregation. Mounting evidence suggests that mitotic chromosome assembly is a progressive, dynamic process that requires topoisomerase II, condensins and cohesin and the activity of several signalling molecules. Current results...

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Detalles Bibliográficos
Autores principales: Moser, Sandra C., Swedlow, Jason R.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078314/
https://www.ncbi.nlm.nih.gov/pubmed/21461697
http://dx.doi.org/10.1007/s10577-011-9198-3
Descripción
Sumario:Proper mitotic chromosome structure is essential for faithful chromosome segregation. Mounting evidence suggests that mitotic chromosome assembly is a progressive, dynamic process that requires topoisomerase II, condensins and cohesin and the activity of several signalling molecules. Current results suggest how these different activities might interact to achieve the familiar form of the mitotic chromosome.