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Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading

OBJECTIVES: SOX9 is a transcription factor that is essential for cartilage extracellular matrix (ECM) formation. Osteoarthritis (OA) is characterised by a loss of cartilage ECM. In chondrocytes SOX9 gene expression is regulated by osmotic loading. Here we characterise SOX9 mRNA regulation through st...

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Detalles Bibliográficos
Autores principales:	Peffers, M.J., Milner, P.I., Tew, S.R., Clegg, P.D.
Formato:	Texto
Lenguaje:	English
Publicado:	W.B. Saunders For The Osteoarthritis Research Society 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078327/ https://www.ncbi.nlm.nih.gov/pubmed/20800688 http://dx.doi.org/10.1016/j.joca.2010.08.011

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