Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells

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Mutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experimental models have shown that interleukin-23 (IL-23) orchestrates innate and T cell-dependent colitis; however, the cell populations it acts on to induce intestinal immune pathology are unknown. Here, using Il...

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Detalles Bibliográficos
Autores principales: Ahern, Philip P., Schiering, Chris, Buonocore, Sofia, McGeachy, Mandy J., Cua, Dan J., Maloy, Kevin J., Powrie, Fiona
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078329/
https://www.ncbi.nlm.nih.gov/pubmed/20732640
http://dx.doi.org/10.1016/j.immuni.2010.08.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078329/
https://www.ncbi.nlm.nih.gov/pubmed/20732640
http://dx.doi.org/10.1016/j.immuni.2010.08.010

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