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A conserved mechanism of DEAD-box ATPase activation by nucleoporins and IP(6) in mRNA export

Superfamily 1 (SF1) and superfamily 2 (SF2) RNA helicases are ubiquitous mRNA-protein (mRNP) remodelling enzymes that play critical roles in all aspects of RNA metabolism1, 2. The SF2 DEAD-box ATPase Dbp5/Ddx19 functions in mRNA export and is thought to remodel mRNPs at the nuclear pore complex (NPC...

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Detalles Bibliográficos
Autores principales:	Montpetit, Ben, Thomsen, Nathan D., Helmke, Kara J., Seeliger, Markus A., Berger, James M., Weis, Karsten
Formato:	Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078754/ https://www.ncbi.nlm.nih.gov/pubmed/21441902 http://dx.doi.org/10.1038/nature09862

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