Targeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis

BACKGROUND: Gene ablation studies have revealed that tumor necrosis factor-related apoptosis-inducing ligand (TRAIL, Apo2L, TNFSF10) plays a crucial role in tumor surveillance, as TRAIL-deficient mice exhibit an increased sensitivity to different types of tumorigenesis. In contrast, possible tumor-p...

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Detalles Bibliográficos
Autores principales: Kedinger, Valerie, Muller, Stephanie, Gronemeyer, Hinrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078898/
https://www.ncbi.nlm.nih.gov/pubmed/21463519
http://dx.doi.org/10.1186/1476-4598-10-34

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