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Vascular Endothelial Growth Factor Receptor-2 Couples Cyclo-Oxygenase-2 with Pro-Angiogenic Actions of Leptin on Human Endothelial Cells

BACKGROUND: The adipocyte-derived hormone leptin influences the behaviour of a wide range of cell types and is now recognised as a pro-angiogenic and pro-inflammatory factor. In the vasculature, these effects are mediated in part through its direct leptin receptor (ObRb)-driven actions on endothelia...

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Detalles Bibliográficos
Autores principales:	Garonna, Elena, Botham, Kathleen M., Birdsey, Graeme M., Randi, Anna M., Gonzalez-Perez, Ruben R., Wheeler-Jones, Caroline P. D.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078934/ https://www.ncbi.nlm.nih.gov/pubmed/21533119 http://dx.doi.org/10.1371/journal.pone.0018823

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