Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome

LC8 dynein light chain (DYNLL) is a eukaryotic hub protein that is thought to function as a dimerization engine. Its interacting partners are involved in a wide range of cellular functions. In its dozens of hitherto identified binding partners DYNLL binds to a linear peptide segment. The known segme...

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Detalles Bibliográficos
Autores principales: Rapali, Péter, Radnai, László, Süveges, Dániel, Harmat, Veronika, Tölgyesi, Ferenc, Wahlgren, Weixiao Y., Katona, Gergely, Nyitray, László, Pál, Gábor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078936/
https://www.ncbi.nlm.nih.gov/pubmed/21533121
http://dx.doi.org/10.1371/journal.pone.0018818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078936/
https://www.ncbi.nlm.nih.gov/pubmed/21533121
http://dx.doi.org/10.1371/journal.pone.0018818

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