Seropositive Myasthenia Gravis Associated with Small-Cell Lung Carcinoma

BACKGROUND: Lambert-Eaton myasthenic syndrome is well known to be a classical paraneoplastic syndrome of small cell lung carcinoma (SCLC). Three cases of seronegative myasthenia gravis (MG) and SCLC were previously reported. CASE REPORT: A 65-year-old man developed a severe progressive respiratory f...

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Detalles Bibliográficos
Autores principales: Ohira, Masayuki, Jeong, Dushin, Oh, Shin J
Formato: Texto
Lenguaje:English
Publicado: Korean Neurological Association 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079160/
https://www.ncbi.nlm.nih.gov/pubmed/21519527
http://dx.doi.org/10.3988/jcn.2011.7.1.43
Descripción
Sumario:BACKGROUND: Lambert-Eaton myasthenic syndrome is well known to be a classical paraneoplastic syndrome of small cell lung carcinoma (SCLC). Three cases of seronegative myasthenia gravis (MG) and SCLC were previously reported. CASE REPORT: A 65-year-old man developed a severe progressive respiratory failure with clinical features of MG. Tests showed a decremental response in the repetitive nerve stimulation test, abnormal single-fiber electromyography, and positive acetylcholine receptor antibody. SCLC was confirmed by the lung biopsy. CONCLUSIONS: This case represents the first case of seropositive MG and SCLC.

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