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CD4(+) T cell help and innate-derived IL-27 induce Blimp-1 dependent IL-10 production by anti-viral CTL
IL-10 is an important regulatory cytokine which can modulate excessive immune mediated injury. Several distinct cell types have been demonstrated to produce IL-10 including most recently CD8(+) cytotoxic T lymphocytes (CTL) responding to respiratory virus infection. Here we report that CD4(+) T cell...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079402/ https://www.ncbi.nlm.nih.gov/pubmed/21297642 http://dx.doi.org/10.1038/ni.1996 |