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Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines
BACKGROUND: We have previously demonstrated that both canine and human OSA cell lines, as well as 8 fresh canine OSA tumor samples, exhibit constitutive phosphorylation of STAT3, and that this correlates with enhanced expression of matrix metalloproteinase-2 (MMP2). While multiple signal transductio...
Autores principales: | Fossey, Stacey L, Bear, Misty D, Kisseberth, William C, Pennell, Michael, London, Cheryl A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079692/ https://www.ncbi.nlm.nih.gov/pubmed/21481226 http://dx.doi.org/10.1186/1471-2407-11-125 |
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