Non-Esterified Fatty Acids Generate Distinct Low-Molecular Weight Amyloid-β (Aβ42) Oligomers along Pathway Different from Fibril Formation

Amyloid-β (Aβ) peptide aggregation is known to play a central role in the etiology of Alzheimer’s disease (AD). Among various aggregates, low-molecular weight soluble oligomers of Aβ are increasingly believed to be the primary neurotoxic agents responsible for memory impairment. Anionic interfaces a...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Bullard, Rebekah L., Patel, Pritesh, Paslay, Lea C., Singh, Dipti, Bienkiewicz, Ewa A., Morgan, Sarah E., Rangachari, Vijayaraghavan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079704/
https://www.ncbi.nlm.nih.gov/pubmed/21526230
http://dx.doi.org/10.1371/journal.pone.0018759

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